Publications

Chanana, V., Hackett, M., Deveci, N., Aycan, N., Ozaydin, B., Cagatay, N. S., Hanalioglu, D., Kintner, D. B., Corcoran, K., Yapici, S., Camci, F., Eickhoff, J., Frick, K. M., Ferrazzano, P., Levine, J. E., & Cengiz, P. (2024). TrkB-mediated sustained neuroprotection is sex-specific and [Formula: see text]-dependent in adult mice following neonatal hypoxia ischemia. Biology of sex differences, 15(1), 1. https://doi.org/10.1186/s13293-023-0057
Chanana, V., Hackett, M., Deveci, N., Aycan, N., Ozaydin, B., Cagatay, N. S., Hanalioglu, D., Kintner, D. B., Corcoran, K., Yapici, S., Camci, F., Eickhoff, J., Frick, K. M., Ferrazano, P., Levine, J. E., & Cengiz, P. (2023). TrkB-mediated sustained neuroprotection is sex-specific and ERα dependent in adult mice following neonatal hypoxia ischemia. Research square, rs.3.rs-3325405. https://doi.org/10.21203/rs.3.rs-3325405/v1
Samuel, A. M., Hacker, L. L., Zebracki, J., Bogenschutz, M. C., Schulz, L., Strayer, J., Vanderloo, J. P., Cengiz, P., & Henderson, S. (2023). Remdesivir Use in Pediatric Patients for SARS-CoV-2 Treatment: Single Academic Center Study. The Pediatric infectious disease journal, 42(4), 310–314. https://doi.org/10.1097/INF.0000000000003814
Taparli, O. E., Shahi, P. K., Cagatay, N. S., Aycan, N., Ozaydin, B., Yapici, S., Liu, X., Cikla, U., Zafer, D., Eickhoff, J. C., Ferrazzano, P., Pattnaik, B. R., & Cengiz, P. (2023). Selectively compromised inner retina function following hypoxic-ischemic encephalopathy in mice: A noninvasive measure of severity of the injury. Neurochemistry international, 163, 105471. https://doi.org/10.1016/j.neuint.2022.105471
Lim, S. Y., & Cengiz, P. (2022). Opioid tolerance and opioid-induced hyperalgesia: Is TrkB modulation a potential pharmacological solution?. Neuropharmacology, 220, 109260. https://doi.org/10.1016/j.neuropharm.2022.109260
Zafer, D., Adams, T., Olson, E., Stenman, L., Taparli, O., Eickhoff, J., Cengiz, P., & Mezu-Ndubuisi, O. J. (2022). Retinal vascular recovery revealed by retinal imaging following neonatal hypoxia ischemia in mice: Is there a role for tyrosine kinase receptor modulation?. Brain research, 1796, 148093. https://doi.org/10.1016/j.brainres.2022.148093
Ozaydin, B., Bicki, E., Taparli, O. E., Sheikh, T. Z., Schmidt, D. K., Yapici, S., Hackett, M. B., Karahan-Keles, N., Eickhoff, J. C., Corcoran, K., Lagoa-Miguel, C., Guerrero Gonzalez, J., Dean Iii, D. C., Sousa, A. M. M., Ferrazzano, P. A., Levine, J. E., & Cengiz, P. (2022). Novel Injury Scoring Tool for Assessing Brain Injury following Neonatal Hypoxia-Ischemia in Mice. Developmental neuroscience, 44(4-5), 394–411. https://doi.org/10.1159/000525244
LaRovere, K. L., Riggs, B. J., Poussaint, T. Y., Young, C. C., Newhams, M. M., Maamari, M., Walker, T. C., Singh, A. R., Dapul, H., Hobbs, C. V., McLaughlin, G. E., Son, M., Maddux, A. B., Clouser, K. N., Rowan, C. M., McGuire, J. K., Fitzgerald, J. C., Gertz, S. J., Shein, S. L., Munoz, A. C., … Overcoming COVID-19 Investigators (2021). Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. JAMA neurology, 78(5), 536–547. https://doi.org/10.1001/jamaneurol.2021.0504
Reddy, P. H., Swerdlow, R. H., Culberson, J., Kang, D., Mitchell, T. L., Smith, Q., Suneja, S., Ory, M. G., Kumar, S., Vijayan, M., Morsy, A., Arandia, G., Lawrence, J. J., George, E., Oliver, D., Pradeepkiran, J. A., Yin, X., Reddy, A. P., Manczak, M., Cengiz, P., … Oddo, S. (2019). Current Status of Healthy Aging and Dementia Research: A Symposium Summary. Journal of Alzheimer’s disease : JAD, 72(s1), S11–S35. https://doi.org/10.3233/JAD-190252
Zafer D, Aycan N, Ozaydin B, Kemanli P, Ferrazzano P, Levine JE, Cengiz P. (2019). Sex differences in Hippocampal Memory and Learning following Neonatal Brain Injury: Is There a Role for Estrogen Receptor-α? Neuroendocrinology, 109(3):249-256. doi: 10.1159/000499661.
Cengiz P, Zafer D, Chandrashekhar JH, Chanana V, Bogost J, Waldman A, Novak B, Kintner DB, Ferrazzano PA. (2019). Developmental differences in microglia morphology and gene expression during normal brain development and in response to hypoxia-ischemia. Neurochemistry International, 127:137-147. doi: 10.1016/j.neuint.2018.12.016.
Chandran R, Kim T, Mehta SL, Udho E, Chanana V, Cengiz P, Kim H, Kim C, Vemuganti R. (2018). A combination antioxidant therapy to inhibit NOX2 and activate Nrf2 decreases secondary brain damage and improves functional recovery after traumatic brain injury. Journal of Cerebral Blood Flow & Metabolism, 38(10):1818-1827. doi: 10.1177/0271678X17738701.
Chanana V, Tumturk A, Kintner D, Udho E, Ferrazzano P, Cengiz P. (2016) Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia. Journal of Visualized Experiments, 25;(116). doi: 10.3791/53695.
Cikla U, Chanana V, Kintner DB, Udho E, Eickhoff J, Sun W, Marquez S, Covert L, Otles A, Shapiro RA, Ferrazzano P, Vemuganti R, Levine JE, Cengiz P. (2016) ERα Signaling Is Required for TrkB-Mediated Hippocampal Neuroprotection in Female Neonatal Mice after Hypoxic Ischemic Encephalopathy (1,2,3). eNeuro. 28;3(1). pii: ENEURO.0025-15.2015. doi: 10.1523/ENEURO.0025-15.2015.
Cikla U, Chanana V, Kintner DB, Covert L, Dewall T, Waldman A, Rowley P, Cengiz P, Ferrazzano P. (2016) Suppression of microglia activation after hypoxia-ischemia results in age-dependent improvements in neurologic injury. Journal of Neuroimmunology. 15;291:18-27. doi: 10.1016/j.jneuroim.2015.12.004.
Li S, Papale LA, Kintner DB, Sabat G, Barrett-Wilt GA, Cengiz P, Alisch RS. (2015) Hippocampal increase of 5-hmC in the glucocorticoid receptor gene following acute stress. Behavioral Brain Research. 1;286:236-40. doi: 10.1016/j.bbr.2015.03.002.
Cengiz P, Zemlan F, Eickhoff JC, Ellenbogen R, Zimmerman JJ. (2015) Increased cerebrospinal fluid cleaved tau protein (C-tau) levels suggest axonal damage in pediatric patients with brain tumors. Child’s Nervous System, 31(8):1313-9. doi: 10.1007/s00381-015-2705-7.
Cengiz P, Kintner DB, Chanana V, Yuan H, Akture E, Kendigelen P, Begum G, Fidan E, Uluc K, Ferrazzano P, Sun D. (2014) Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation. PLoS One. 2;9(1):e84294.
Uluc K, Kendigelen P, Fidan E, Zhang L, Chanana V, Kintner D, Akture E, Song C, Ye K, Sun D, Ferrazzano P, Cengiz P. (2013) TrkB Receptor Agonist 7, 8 Dihydroxyflavone Triggers Profound Gender- Dependent Neuroprotection in Mice After Perinatal Hypoxia and Ischemia. CNS & Neurological Disorders – Drug Targets. 12(3):360-70.
Ferrazzano P, Chanana V, Uluc K, Fidan E, Akture E, Kintner DB, Cengiz P, Sun D. (2013) Age-dependent microglial activation in immature brains after hypoxia- ischemia. CNS & Neurological Disorders – Drug Targets. 12(3):338-49.
Shi Y, Yuan H, Kim D, Chanana V, Baba A, Matsuda T, Cengiz P, Ferrazzano P, Sun D. (2013) Stimulation of Na(+)/H(+) exchanger isoform 1 promotes microglial migration. PLoS One. 21;8(8):e74201.
Cengiz P, Uluc K, Kendigelen P, Akture E, Hutchinson E, Song C, Zhang L, Lee J, Budoff GE, Meyerand E, Sun D, Ferrazzano P. (2011) Chronic neurological deficits in mice after perinatal hypoxia and ischemia correlate with hemispheric tissue loss and white matter injury detected by MRI. Developmental Neuroscience. 33(3-4):270-9.
Cengiz P, Kleman N, Uluc K, Kendigelen P, Hagemann T, Akture E, Messing A, Ferrazzano P, Sun D. (2011) Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury. Antioxidants & Redox Signaling. 14(10):1803-13.
Liu Y, Kintner DB, Begum G, Algharabli J, Cengiz P, Shull GE, Liu XJ, Sun D. (2010) Endoplasmic reticulum Ca2+ signaling and mitochondrial Cyt c release in astrocytes following oxygen and glucose deprivation. Journal of Neurochemistry. 1;114(5):1436-46.